Natural Medicine Research – Liver Detox

  1. Water extracts of thyme and ginger have detoxifying and antioxidant effects, it is recommended to use them to avoid alcohol toxicity. Food Chem Toxicol. 2009 Aug;47(8):1945-9
  2. Isoflavones are thought to be biologically active components in soy that play a role in the prevention of chronic diseases including cancer.  One study concluded that the induction of a liver enzyme known as NOQ1 may be one mechanism by which dietary genistein improves the capacity of the liver to detoxify carcinogens.Cancer Genomics Proteomics. 2009 Mar-Apr;6(2):85-92.
  3. A study on long term use of milk thistle in rats found a decrease in spontaneous background tumors including mammary gland tumors in female rats and liver tumors in male mice.Toxicol Pathol February 2011 vol. 39 no. 2 398-409
  4. Induction of phase 2 liver detoxication enzymes is a powerful strategy for achieving protection against cancer and free radicals. A number of edible plants contain substantial quantities of compounds that regulate mammalian enzymes of xenobiotic metabolism. Edible plants belonging to the family Cruciferae and genus Brassica (e.g., broccoli and cauliflower) contain substantial quantities of isothiocyanates (mostly in the form of their glucosinolate precursors) some of which (e.g., sulforaphane or 4-methylsulfinylbutyl isothiocyanate) are very potent inducers of phase 2 enzymes.  Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10367-72.